Education:

09/2019-11/2020 Visiting Scholar inUniversity of California RiversideCollege of chemistry and chemical engineering

6/2018 PhD of AnalyticalChemistry,College of chemistry and chemical engineering, State Key Laboratory of Chemo/Biosensing and Chemo-metrics,Hunan University, Changsha

10/2015-6/2018Doctoral student, Department ofChemistry,Tsinghua University,Beijing

09/2000-06/2003 Master of Analytical Chemistry, College of chemistry and chemical engineering, State Key Laboratory of Chemo/Biosensing and Chemo-metrics,Hunan University, Changsha

6/1995 Bachelor ofChemistry,College ofChemistry,Hunan university of Humanities, Science andTechnology.

Academic Appointments:

9/2003-Present Department ofPharmacy,University of South China, Hengyang, Hunan Province, China

Publications in recent years:

(1)Kaiyue Wu,Miaojia Chen,Xiaoyu Peng,Yang Li,Guotao Tang,Junmei Peng,Xuan Cao*.Recent progress of research onthe benzimidazole PARP-1 inhibitors, Mini-Reviews in Medicinal Chemistry. 2022 (accepted and to be published)(IF=?)

(2)Kaiyue Wu,Xiaoyu Peng,Miaojia Chen,Yang Li,Guotao Tang,Junmei Peng,Yuanyuan Peng,Xuan Cao*.Recent progress of research on anti-tumoragents usingbenzimidazole as the structure unit, Chem. Biol. Drug Des. 2022, 00:1-22. DOI:10.1111/cbdd.14022 (IF=?)

(3) Miaojia Chen, Honglin Huang, Kaiyue Wu, Guotao Tang, Junmei Peng,Xuan Cao*.Synthesis and evaluation of2-(4-[4-acetylpiperazine-1-carbonyl] phenyl)-1H-benzo[d]imidazole-4-carboxamide derivatives as potential PARP-1 inhibitors and preliminary study on structure-activity relationship, Drug Development Research, 2021, 83(8): 1-9.DOI:10.1002/ddr.21843(IF=4.360)

(4) Jinmei Qiu, Changfeng Qin, Shengen Wu, Tongying Ji, Guotao Tang, Xiaoyong Lei,Xuan Cao*, Zhizhong Xie*.A novel salvianolic acid A analog with resveratrol structure and its antioxidant activities in vitro and invivo，Drug Development Research, 2020, 82(6): 108-114.DOI:10.1002 /ddr.21734(IF=4.360)

(5)Jingjing Feng^#,Xuan Cao^#(co-author), Qi Pan, Yan He.* Direct observation of Single Plasmonic Metal Nanoparticle Reaction in Microcolumn with Chromatic-Aberration-Free Laser Light-Sheet Scattering Imaging.Electrophoresis, 2019, 40(13):1747-1753 DOI: 10.1002/elps.201900071(IF=3.08)

(6)Xuan Cao^#, Gang Lei, Jing Jing Feng, Qi Pan,YanHe.* A Novel Color Modulation Analysis Strategy through Tunable Multiband Laser for Nanoparticle Identification and Evaluation,Anal. Chem., 2018, 90(4):2501-2507. DOI:10.1021/acs.analchem. 7b03636(IF=6.042)

(7)Xuan Cao, Jingjing Feng, Qi Pan, Bin Xiong, Yan He,* and EdwardS. Yeung. Direct Imaging of Single Plasmonic Metal Nanoparticles inCapillary with Laser Light-Sheet Scattering Imaging. Anal. Chem., 2017. 89(2):2692-2697. DOI:10.1021 /acs.analchem.6b03844(IF=6.320)

(8)Xiaodong Cheng,Xuan Cao, Bin Xiong,YanHe,* and Edward S.Yeung.Background-free three-dimensional selective imaging of anisotropic plasmonic nanoparticles.Nano Res., 2017. 10(4):1423-1433.

DOI: 10.1007/s12274-017-1524-4(IF=7.354)

(9)Lan Peng,Xuan Cao, Bin Xiong,*YanHe* and Edward S.Yeung.A novel scattering switch-on detection technique for target-induced plasmon-coupling based sensing by single-particle opticalanisotropy imaging. Chem Commun., 2016, 52(2):7616-7619. DOI: 10.1039/ c6cc02536f(IF=6.567)

Research Interest

Pharmaceutical chemistry

1)Design and totally synthesize potential PARP1 inhibitor

2)Natural anti-tumoragents such asSalvianolicAcid A analogs.